Type 1 vs Type 2 Diabetes: A Fundamental Difference Type 2 Diabetes Insulin is still produced (at least initially) There is insulin resistance GLP-1 agonists stimulate insulin secretion (in a glucose-dependent way) Type 1 Diabetes The pancreas produces little to no insulin Insulin must be given externally There is no reserve safety net In Type 1 diabetes, insulin is not just for glucose control it is a critical anti-ketogenic hormone
The body cannot produce vitamin B12 independently, so it must be obtained through dietary sources such as meat, fish, dairy products, and fortified foods, or via supplementation
For now, MOTS-c should be viewed as a scientific breakthrough still in development , with applications that may one day impact medicine, sports performance, and longevity but not as a current therapeutic or supplement.
J Clin Invest (1983) 72(3):115062
T2DM and obesity are grouped in MetS, a complex disorder characterized by at least three of the following criteria: abdominal adiposity, IR, hypertension, hypercholesterolemia, and hypertriglyceridemia (Monserrat-Mesquida et al., 2020)
Most people can get enough vitamin B12 in foods they eat already, such as fish, meat poultry, eggs, dairy products, and foods that are fortified with B12 (like some breakfast cereals)